A streamlined, specialized process for heroin production summarized in the following steps. Although heroin’s logP is close to 2 – the ideal value for CNS drugs – the difference between it and morphine, 0.7 doesn’t seem like a big deal. But keep in mind that a 0.7 log10 unit difference means that heroin is 6.5-times more lipophilic than morphine, so it gets […]

Content Alcohol Tolerance and Changes in the Brain Learned Tolerance Environmental-dependent tolerance What is Alcohol Tolerance? Chronic Alcoholism Many other factors, such as drinking habits, can influence functional tolerance. But it is possible to reverse even a high alcohol tolerance in about a month. Drinking regularly will lead to an increase in tolerance to the […]